ANTI-INFLAMMATORY ACTIVITY OF ROOT OF SOLANUM MELONGENA.

Anti-inflammatory activity of the petroleum ether, chloroform, Aqueous and methanol extracts of the root of Solanum melongena was studied in Wistar rats using the carrageenan induced left hind paw edema. The petroleum ether, chloroform, aqueous and methanol extracts at a dose of 300, 400, 500 and 500 mg/kg body wt. shows moderate to significant anti-inflammatory activity. The petroleum ether, chloroform, aqueous and methanol extracts of Solanum melongena reduced the edema induced by carrageenan by 68%, 53%, 74% and 47% respectively on oral administration of 300, 400, 500 and 500 mg/kg body wt., as compared to the untreated control group. Diclofenac sodium at 20 mg/kg body wt. inhibited the edema volume by 79%. The results indicated that the petroleum ether and aqueous extract shows more significant anti-inflammatory activity then chloroform and methanol extracts when compared with the standard and untreated control.