A Multiple Dose Phase 1 Assessment of Rilpivirine Long-Acting in a Model of Pre-Exposure Prophylaxis against HIV

Ross D. Cranston,Charlene S. Dezzutti,Aaron Siegel,Jarret Engstrom,Cory Shetler,Nicola Richardson-Harman,Kaleab Z. Abebe,David Back,Laura Else,Deidre Egan,Saye Khoo,James E. Egan,Ron Stall,Peter Williams,Rhonda M. Brand,Urvi M. Parikh,Ian McGowan

A Multiple Dose Phase 1 Assessment of Rilpivirine Long-Acting in a Model of Pre-Exposure Prophylaxis against HIV

2019

Ross D. Cranston
Charlene S. Dezzutti
Aaron Siegel
Jarret Engstrom
Cory Shetler
Nicola Richardson-Harman
Kaleab Z. Abebe
David Back
Laura Else
Deidre Egan
Saye Khoo
James E. Egan
Ron Stall
Peter Williams
Rhonda M. Brand
Urvi M. Parikh
Ian McGowan

Abstract The MWRI-01 study characterized the safety, acceptability, pharmacokinetic (PK), and pharmacodynamic (PD) profile of rilpivirine (RPV) long acting (LA) in a model of preexposure prophylaxi...

Keywords:

Biology
Pre-exposure prophylaxis
Virology
Oncology
Rilpivirine
Internal medicine
Pharmacodynamics
multiple dose
long acting
Rectum
Pharmacology
human immunodeficiency virus
Pharmacokinetics

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