Identification of the isotherm function in chromatography using CMA-ES
2007
This paper deals with the identification of the flux for a system of conservation laws in the specific example of analytic chromatography. The fundamental equations of chromatographic process are highly non linear. The state-of-the-art evolution strategy, CMA-ES (the covariance matrix adaptation evolution strategy), is used to identify the parameters of the so-called isotherm function. The approach was validated on different configurations of simulated data using either one, two or three components mixtures. CMA-ES is then applied to real data cases and its results are compared to those of a gradient-based strategy.
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