Biodegradable, flexible silicon nanomembrane-based NOx gas sensor system with record-high performance for transient environmental monitors and medical implants

A novel transient electronics technology that is capable of completely dissolving or decomposing in certain conditions after a period of operation offers unprecedented opportunities for medical implants, environmental sensors, and other applications. Here, we describe a biodegradable, flexible silicon-based electronic system that detects NO species with a record-breaking sensitivity of 136 Rs (5 ppm, NO2) and 100-fold selectivity for NO species over other substances with a fast response (~30 s) and recovery (~60 s). The exceptional features primarily depend on not only materials, dimensions, and design layouts but also temperatures and electrical operations. Large-scale sensor arrays in a mechanically pliable configuration exhibit negligible deterioration in performance under various modes of applied loads, consistent with mechanics modeling. In vitro evaluations demonstrate the capability and stability of integrated NOx devices in severe wet environments for biomedical applications. Degradable devices that monitor health by measuring gases emitted by the body have been developed by researchers in South Korea, the UK and the USA. Biodegradable electronics, devices that decay naturally over time, are potentially useful for medical devices. They can be used internally as implants that don’t need to be surgically removed or externally as wearable health monitors. Chong-Yun Kang and Suk-Won Hwang from Korea University in Seoul and their colleagues have developed a biodegradable, flexible silicon nanomembrane to detect nitric oxide with a high sensitivity andselectivity and a fast response time. Nitric oxide sensors are important for health monitoring as the gas is associated with many physiological processes including regulation of the vascular system and blood flow. In vitro experiments in aqueous solutions demonstrated the feasibility of their devices for disposable medical implants. Soft, transient silicon-based gas sensing system capable of detecting nitrogen oxides with remarkable sensitivity and selectivity is presented in this report. The results provide materials, device layouts, manufacturing process, and theorectical modeling illlustrating the capabilities and operational aspects. In vitro experiments demonstrate the possibilities for disposable environmental monitors and temporary biomedical implants.