Polymer Amplified Enantioselectivity in the Fluorescent Recognition of Prolinol

A 1,1'-bi-2-naphthol (BINOL)-aldehyde-based polymer (S)-6 is synthesized which has exhibited enantioselective fluorescent enhancement toward prolinol. It is found that the polymer shows greatly amplified enantioselectivity over the corresponding small molecular sensor under the same conditions. This is attributed to the PET processes between the BINOL units in the polymer chain as well as the different steric environment provided by the polymer.