Pyridinolysis of Diethyl Phosphinic Chloride in Acetonitrile

o C to gain further information of mechanism. The pyridinolyses of eleven R1R2P(=O or S)Cl-type substrates in MeCN (eq 1) are reviewed to obtain systematic information on phosphoryl transfer reaction mechanism. The kinetic results are discussed on the bases of thio effect on reactivity, steric effect of R1 and R2 on reactivity of substrate, electrophilicity of substrate, comparison between anilinolysis and pyridinolysis, and pyridinolysis mechanism. Eleven R1R2P(=O or S)Cl-type substrates are as follows: dimethyl phosphinic chloride (1O); 1h