Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion

Mingxia Liu,Soonkyu Chung,Gregory S. Shelness,John S. Parks

Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion

2017

Mingxia Liu
Soonkyu Chung
Gregory S. Shelness
John S. Parks

Abstract ATP binding cassette transporter A1 (ABCA1) is a membrane transporter that facilitates nascent HDL formation. Tangier disease subjects with complete ABCA1 deficiency have

Keywords:

Biochemistry
Tangier disease
Golgi apparatus
Apolipoprotein B
ABCA1
Biology
Secretion
Endocrinology
Internal medicine
Transporter
Endoplasmic reticulum
VLDL triglyceride

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