Identification of differentially expressed genes in human varicose veins: involvement of matrix gla protein in extracellular matrix remodeling.

Chrystelle Cario-Toumaniantz,Cédric Boularan,Leon J. Schurgers,Marie-Françoise Heymann,Martine Le Cunff,Jean-J. Leger,Gervaise Loirand,Pierre Pacaud

Identification of differentially expressed genes in human varicose veins: involvement of matrix gla protein in extracellular matrix remodeling.

2007

Chrystelle Cario-Toumaniantz
Cédric Boularan
Leon J. Schurgers
Marie-Françoise Heymann
Martine Le Cunff
Jean-J. Leger
Gervaise Loirand
Pierre Pacaud

This study was designed to identify the global pattern of differentially expressed genes in human varicose veins. Using suppressive subtractive hybridization, we identified overexpression of genes kno

Keywords:

Varicose veins
Suppression subtractive hybridization
Gene expression
Anatomy
Vascular disease
Tissue inhibitor of metalloproteinase
Extracellular matrix
Gene
Matrix gla protein
Biology
Cell growth
Vascular smooth muscle

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