Two new flavanone glycosides from Scutellaria galericulata with anti-inflammatory activities

Abstract Two new flavanone glycosides, named scugalerosides A and B ( 1 - 2 ), were isolated from the whole plant of Scutellaria galericulata . Their chemical structures including absolute configurations were established on the basis of detailed physical data analyses. In vitro , two new compounds showed anti-inflammatory activities, with the inhibition rates of release of β -glucuronidase from polymorphonuclear leukocytes of rats being 43.7% and 45.1% at concentrations of 10  μ M.