Enantioselective intermolecular iodoacetalization of enol ethers catalyzed by chiral Co(III)-complex-templated Brønsted acids

Abstract The chiral Co(III)-complex-templated Bronsted acids were used as efficient bifunctional phase-transfer catalysts for the asymmetric intermolecular iodoacetalization of enol ethers, such as 3,4-dihydro-2H-pyran, 2,3-dihydrofuran, ethyl vinyl ether with alcohols and NIS, furnishing the 3-iodoacetals in high yield with up to 83:17 er.