A Strategy for Co-former Selection to Design Stable Co-amorphous Formations Based on Physicochemical Properties of Non-steroidal Inflammatory Drugs

Hiroshi Ueda,Noriyuki Muranushi,Satoshi Sakuma,Yasuo Ida,Takeshi Endoh,Kazunori Kadota,Yuichi Tozuka

A Strategy for Co-former Selection to Design Stable Co-amorphous Formations Based on Physicochemical Properties of Non-steroidal Inflammatory Drugs

2016

Hiroshi Ueda
Noriyuki Muranushi
Satoshi Sakuma
Yasuo Ida
Takeshi Endoh
Kazunori Kadota
Yuichi Tozuka

Purpose This study aimed to investigate the physicochemical factors contributing to stable co-amorphous formations and to design a co-former selection strategy.

Keywords:

Amorphous solid
Crystallization
Chemistry
Organic chemistry
Glass transition
non steroidal
intermolecular interaction
selection strategy

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