Detection and comparison of physiological indexes in the wild and laboratory tree shrew
2011
To provide fundamental basis for the tree shrew models of human
diseases, we examined and compared the physiological and biochemical
indexes between wild and laboratory tree shrews. Blood samples were
taken from 54 wild tree shrews that were housed in laboratory for 1
− 2 months, and from 54 first-generation of the laboratory tree
shrews; each group had nearly equal male and female composition. Some
of the first reported physiological and biochemical indexes were showed
no significant differences between genders, and these indexes in
laboratory tree shrews were as follows [medium (inter-quartile range)
]: CK 1449 (956) U/L, CTNI 5.94 (7.23) μg/L, TBA15.6 (19.7)
μmol/L, FRUC 393.5 (80.8) μmol/L and LDL-C0.36 (0.32); and in
the wild tree shrews, 986 (564) U/L, 4.01 (4.10) μg/L, 20.0 (20.6)
μmol/L, 379.0 (104.0) μmol/L and 0.46 (0.23) mmol/L,
respectively. In the laboratory tree shrews, the variations of
physiological and biochemical indexes were smaller, but the mean values
of some indicators related to liver and heart functions became higher.
These data would be valuable for the development of tree shrew models
of human diseases.
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