A novel iridium(III) complex for sensitive HSA phosphorescence staining in proteome research

We report a novel organo-iridium(III) complex (Ir1) for the selective and sensitive determination of human serum albumin (HSA). The phosphorescence of Ir1 is turned-on by HSA in the urinary system. Importantly, Ir1 is much simpler and less time-consuming for HSA staining than Coomassie blue in proteomics studies.