Intra-Urban Exposure to PM2.5 in Mexico City Associated with Acute Cardiovascular and Cerebrovascular Mortality from 2004-2013

Background. Limited evidence exists about short-term exposure to different intra-urban concentration levels and composition of particulate matter with aerodynamic diameter ≤2.5µm (PM2.5) associated with acute cardiovascular and cerebrovascular mortality.Methods. We used an ecologic approach and Generalized Linear Mixed Models (GLMM) with Poisson regressions in order to assess daily exposure to PM2.5 associated with all cardiovascular, all cerebrovascular and ischemic heart mortality in people ≥25 and ≥65 years for each one of the sixteen boroughs of Mexico City for the period from 2004-2013. Exposure to PM2.5 was evaluated with estimates from a new hybrid spatiotemporal model using satellite measurements of Aerosol Optical Depth (AOD-PM2.5) with resolution of 1 km2 from NASA for same day exposure (lag0), and average of the current and previous day (lag0-1). The high spatial resolution of this model also allowed for the daily borough-level PM2.5 mean estimates to be weighted to account fo...