Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma

Yu Cao,Katherine K. Green,Steve Quattlebaum,Ben Milam,Ling Lu,Dexiang Gao,Hui He,Ningning Li,Liwei Gao,Francis Hall,Matthew Whinery,Elyse Handley,Yi Ma,Tao Xu,Feng Jin,Jing Xiao,Minjie Wei,Derek E. Smith,Sophia Bornstein,Neil D. Gross,Dohun Pyeon,John I. Song,Shi-Long Lu

Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma

2018

Background To identify aberrant promoter methylation of genomic loci encoding microRNA (mgmiR) in head and neck squamous cell carcinoma (HNSCC) and to evaluate a biomarker panel of mgmiRs to improve the diagnostic accuracy of HNSCC in tissues and saliva.

Keywords:

Cancer research
DNA methylation
Locus (genetics)
Human genetics
Biomarker (medicine)
Saliva
Head and neck squamous-cell carcinoma
Biology
microRNA
Methylation
Cell culture

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