α5GABA A subunit-containing receptors and sweetened alcohol cue-induced reinstatement and active sweetened alcohol self-administration in male rats

Cassie M. Chandler,Jaren Reeves-Darby,Sherman A. Jones,J. Abigail McDonald,Guanguan Li,Toufiqur Rahman,James M. Cook,Donna M. Platt

α5GABA A subunit-containing receptors and sweetened alcohol cue-induced reinstatement and active sweetened alcohol self-administration in male rats

2019

Cassie M. Chandler
Jaren Reeves-Darby
Sherman A. Jones
J. Abigail McDonald
Guanguan Li
Toufiqur Rahman
James M. Cook
Donna M. Platt

Rationale GABAA receptors containing the α5 subunit (i.e., α5GABAA receptors) appear to be critically involved in the reinforcing and subjective effects of alcohol. Their role in alcohol relapse remains unknown.

Keywords:

Self-administration
Internal medicine
Endocrinology
Ethanol
Psychology
GABAA receptor
Protein subunit
Alcohol cue
Alcohol
Receptor
Stimulus (physiology)
Agonist
Inverse agonist
Naltrexone

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