Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Stephanie L. Schmit,Christopher K. Edlund,Fredrick R. Schumacher,Jian Gong,Tabitha A. Harrison,Jeroen R. Huyghe,Chenxu Qu,Marilena Melas,David Van Den Berg,Hansong Wang,Stephanie Tring,Sarah J. Plummer,Demetrius Albanes,M. Henar Alonso,Christopher I. Amos,Kristen Anton,Aaron K. Aragaki,Volker Arndt,Elizabeth L. Barry,Sonja I. Berndt,Stéphane Bézieau,Stephanie A. Bien,Amanda Bloomer,Juergen Boehm,Marie Christine Boutron-Ruault,Hermann Brenner,Stefanie Brezina,Daniel D. Buchanan,Katja Butterbach,Bette J. Caan,Peter T. Campbell,Chris S. Carlson,Jose E. Castelao,Andrew T. Chan,Jenny Chang-Claude,Stephen J. Chanock,Iona Cheng,Ya Wen Cheng,Lee Soo Chin,James M. Church,Timothy R. Church,Gerhard A. Coetzee,Michelle Cotterchio,Marcia Cruz–Correa,Keith R. Curtis,David Duggan,Douglas F. Easton,Dallas R. English,Edith J. M. Feskens,Rocky Fischer,Liesel M. FitzGerald,Barbara K. Fortini,Lars G. Fritsche,Charles S. Fuchs,Manuela Gago-Dominguez,Manish Gala,Steven Gallinger,W. James Gauderman,Graham G. Giles,Edward Giovannucci,Stephanie M. Gogarten,Clicerio González Villalpando,Elena M. Gonzalez-Villalpando,William M. Grady,Joel K. Greenson,Andrea Gsur,Marc J. Gunter,Christopher A. Haiman,Jochen Hampe,Sophia Harlid,John F. Harju,Richard B. Hayes,Philipp Hofer,Michael Hoffmeister,John L. Hopper,Shu-Chen Huang,José María Huerta,Thomas J. Hudson,David J. Hunter,Gregory Idos,Motoki Iwasaki,Rebecca D. Jackson,Eric J. Jacobs,Sun Ha Jee,Mark A. Jenkins,Weihua Jia,Shuo Jiao,Amit D. Joshi,Laurence N. Kolonel,Suminori Kono,Charles Kooperberg,Vittorio Krogh,Tilman Kuehn,Sébastien Küry,Andrea Z. LaCroix,Cecelia A. Laurie,Flavio Lejbkowicz,Mathieu Lemire,Heinz-Josef Lenz,David N. Levine,Christopher I. Li,Li Li,Wolfgang Lieb,Yi Lin,Noralane M. Lindor,Yun-Ru Liu,Fotios Loupakis,Yingchang Lu,Frank Luh,Jing Ma,Christoph Mancao,Frank J. Manion,Sanford D. Markowitz,Vicente Martín,Koichi Matsuda,Keitaro Matsuo,Kevin McDonnell,Caroline McNeil,Roger L. Milne,Antonio J. Molina,Bhramar Mukherjee,Neil Murphy,Polly A. Newcomb,Kenneth Offit,Hanane Omichessan,Domenico Palli,Jesús P. Paredes-Cotoré,Julyann Pérez-Mayoral,Paul D.P. Pharoah,John D. Potter,Conghui Qu,Leon Raskin,Gad Rennert,Hedy S. Rennert,Bridget M. Riggs,Clemens Schafmayer,Robert E. Schoen,Thomas A. Sellers,Daniela Seminara,Gianluca Severi,Wei Shi,David Shibata,Xiao-Ou Shu,Erin M. Siegel,Martha L. Slattery,Melissa C. Southey,Zsofia K. Stadler,Mariana C. Stern,Sebastian Stintzing,Darin Taverna,Stephen N. Thibodeau,Duncan C. Thomas,Antonia Trichopoulou,Shoichiro Tsugane,Cornelia M. Ulrich,Fränzel J.B. Van Duijnhoven,Bethany van Guelpan,Joseph Vijai,Jarmo Virtamo,Stephanie J. Weinstein,Emily White,Aung Ko Win,Alicja Wolk,Michael O. Woods,Anna H. Wu,Kana Wu,Yong-Bing Xiang,Yun Yen,Brent W. Zanke,Yi Xin Zeng,Ben Zhang,Niha Zubair,Sun-Seog Kweon,Jane C. Figueiredo,Wei Zheng,Loic Le Marchand,Annika Lindblom,Victor Moreno,Ulrike Peters,Graham Casey,Li Hsu,David V. Conti,Stephen B. Gruber

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

2019

Stephanie L. Schmit
Christopher K. Edlund
Fredrick R. Schumacher
Jian Gong
Tabitha A. Harrison
Jeroen R. Huyghe
Chenxu Qu
Marilena Melas
David Van Den Berg
Hansong Wang
Stephanie Tring
Sarah J. Plummer
Demetrius Albanes
M. Henar Alonso
Christopher I. Amos
Kristen Anton
Aaron K. Aragaki
Volker Arndt
Elizabeth L. Barry
Sonja I. Berndt
Stéphane Bézieau
Stephanie A. Bien
Amanda Bloomer
Juergen Boehm
Marie Christine Boutron-Ruault
Hermann Brenner
Stefanie Brezina
Daniel D. Buchanan
Katja Butterbach
Bette J. Caan
Peter T. Campbell
Chris S. Carlson
Jose E. Castelao
Andrew T. Chan
Jenny Chang-Claude
Stephen J. Chanock
Iona Cheng
Ya Wen Cheng
Lee Soo Chin
James M. Church
Timothy R. Church
Gerhard A. Coetzee
Michelle Cotterchio
Marcia Cruz–Correa
Keith R. Curtis
David Duggan
Douglas F. Easton
Dallas R. English
Edith J. M. Feskens
Rocky Fischer
Liesel M. FitzGerald
Barbara K. Fortini
Lars G. Fritsche
Charles S. Fuchs
Manuela Gago-Dominguez
Manish Gala
Steven Gallinger
W. James Gauderman
Graham G. Giles
Edward Giovannucci
Stephanie M. Gogarten
Clicerio González Villalpando
Elena M. Gonzalez-Villalpando
William M. Grady
Joel K. Greenson
Andrea Gsur
Marc J. Gunter
Christopher A. Haiman
Jochen Hampe
Sophia Harlid
John F. Harju
Richard B. Hayes
Philipp Hofer
Michael Hoffmeister
John L. Hopper
Shu-Chen Huang
José María Huerta
Thomas J. Hudson
David J. Hunter
Gregory Idos
Motoki Iwasaki
Rebecca D. Jackson
Eric J. Jacobs
Sun Ha Jee
Mark A. Jenkins
Weihua Jia
Shuo Jiao
Amit D. Joshi
Laurence N. Kolonel
Suminori Kono
Charles Kooperberg
Vittorio Krogh
Tilman Kuehn
Sébastien Küry
Andrea Z. LaCroix
Cecelia A. Laurie
Flavio Lejbkowicz
Mathieu Lemire
Heinz-Josef Lenz
David N. Levine
Christopher I. Li
Li Li
Wolfgang Lieb
Yi Lin
Noralane M. Lindor
Yun-Ru Liu
Fotios Loupakis
Yingchang Lu
Frank Luh
Jing Ma
Christoph Mancao
Frank J. Manion
Sanford D. Markowitz
Vicente Martín
Koichi Matsuda
Keitaro Matsuo
Kevin McDonnell
Caroline McNeil
Roger L. Milne
Antonio J. Molina
Bhramar Mukherjee
Neil Murphy
Polly A. Newcomb
Kenneth Offit
Hanane Omichessan
Domenico Palli
Jesús P. Paredes-Cotoré
Julyann Pérez-Mayoral
Paul D.P. Pharoah
John D. Potter
Conghui Qu
Leon Raskin
Gad Rennert
Hedy S. Rennert
Bridget M. Riggs
Clemens Schafmayer
Robert E. Schoen
Thomas A. Sellers
Daniela Seminara
Gianluca Severi
Wei Shi
David Shibata
Xiao-Ou Shu
Erin M. Siegel
Martha L. Slattery
Melissa C. Southey
Zsofia K. Stadler
Mariana C. Stern
Sebastian Stintzing
Darin Taverna
Stephen N. Thibodeau
Duncan C. Thomas
Antonia Trichopoulou
Shoichiro Tsugane
Cornelia M. Ulrich
Fränzel J.B. Van Duijnhoven
Bethany van Guelpan
Joseph Vijai
Jarmo Virtamo
Stephanie J. Weinstein
Emily White
Aung Ko Win
Alicja Wolk
Michael O. Woods
Anna H. Wu
Kana Wu
Yong-Bing Xiang
Yun Yen
Brent W. Zanke
Yi Xin Zeng
Ben Zhang
Niha Zubair
Sun-Seog Kweon
Jane C. Figueiredo
Wei Zheng
Loic Le Marchand
Annika Lindblom
Victor Moreno
Ulrike Peters
Graham Casey
Li Hsu
David V. Conti
Stephen B. Gruber

Background: Previous genome-wide association studies (GWAS) have identified 42 loci (P < 5x10(-8)) associated with risk of colorectal cancer (CRC). Expanded consortium efforts facilitating the d ...

Keywords:

Genetic predisposition
Colorectal cancer
Genetics
Biology
Locus (genetics)

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