Direct hydroxylation of benzene to phenol mediated by nanosized vanadium oxide cluster ions at room temperature

Gas-phase vanadium oxide cluster cations and anions are prepared by laser ablation. The small cluster ions ( 1000 amu) with no mass selection are reacted with C6H6 in a fast flow reactor. Rich product variety is encountered in these reactions, and the reaction channels for small cationic and anionic systems are different. For large clusters, the reactivity patterns of (V2O5)n+ (n = 6-25) and (V2O5)nO− (n = 6-24) cluster series are very similar to each other, indicating that the charge state has little influence on the oxidation of benzene. In sharp contrast to the dramatic changes of reactivity of small clusters, a weakly size dependent reaction behavior of large (V2O5)6-25+ and (V2O5)6-24O− clusters is observed. Therefore, the charge state and the size are not the major factors influencing the reactivity of nanosized vanadium oxide cluster ions toward C6H6, which is not commo...