Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood–brain barrier
2018
The blood–brain barrier (BBB), which imposes significant water permeability restriction, effectively isolates the brain from the systemic circulation. Seemingly paradoxical, the abundance of aquaporin-4 (AQP-4) on the inside of the BBB strongly indicates the presence of unique water dynamics essenti
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