Analysis of drug resistance echinocandin type

2006 
A nucleic acid assay for drug resistance echinocandin type susceptible fungi losfarmacos the echinocandin type containing the corresponding FKS1 subunit 1 - 3β - D - glucan synthase of Fks1p consisting of a first target nucleic acid sequence the FKS1correspondiente gene to amino acids 636-654 of CaFks1p or smaller of that sequence queincluya amino acids 641-649 to generate a first amplified target sequence with probes specific hibridacionmarcadas for the amino acid mutations S645P, S645Y and S645F of CaFks1p area, and presentade detect any of these mutations in said first amplified target sequence.
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