Synthesis of glucuronides of multidrug resistance reversing drug MS-209
1999
Abstract We synthesized the glucuronides of MS-209 to identify the two main unknown metabolites in human urine. Reaction of MS-209 and glucuronyl trichloroacetimidate gave two β-isomers, which were each glucuronate of ( R )- and ( S )-MS-209. These spectrum data were identical with the metabolites.
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