WhiB6 is required for the secretion-dependent regulation of ESX-1 substrates in pathogenic mycobacteria.

We thank Astrid van der Sar and Esther Stoop for providing the M. marinum E11 ESX-1 mutants. Work in AP’s laboratory is supported by the KAUST faculty baseline fund (BAS/1/1020-01-01). The authors thank members of the Bioscience Core Lab (BCL) at KAUST for sequencing the RNA-seq libraries on the Illumina Hiseq platform and for running protein samples through the quantitative proteomics workflow with the LTQ Orbitrap Velos instrument (Thermo Scientific).