Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy
2012
In mouse models, the authors find that NRG1–ErbB4 signaling contributes to epilepsy through regulating the excitability of fast-spiking parvalbumin interneurons. ErbB4 expression was also reduced in human epileptogenic tissue.
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