Extraction of flutamide from aqueous solutions

: The objective of the present study was to elucidate peculiarities of flutamide extraction from aqueous solutions using he liquid-liquid extraction technique and spectrophotometry in the visible spectrum. The results of flutamide extraction were shown to depend on the chemical nature of the extractant, pH of the aqueous phase as well as its saturation with water and electrolytes. The study has demonstrated that the optimal conditions for flutamide extraction by ethylacetate are created by using the aqueous phase with the pH values in the range from 1.0 to 12.0. We have calculated extraction factor necessary for the luberation of the desired amount of flutamide from the aqueous solutions with the use of a concrete solvent.