Method for preparing 4-chlorine-2-(trifluoroacetyl) aniline hydrochloride hydrate

The invention discloses a method for preparing a 4-chlorine-2-(trifluoroacetyl) aniline hydrochloride hydrate, and belongs to the field of compound synthesis. P-chloroaniline serves as a raw material, the method includes the following steps that 1, the p-chloroaniline and acid anhydride are reacted to obtain 4-chlorine-N-phthaloyl aniline; 2, the 4-chlorine-N-phthaloyl aniline and trifluoroacetic acid ethyl ester are reacted under the effect of butyl lithium to obtain N-(4-chlorine-2 trifluoroacetyl phenyl)-phthalic diamide; 3, after the N-(4-chlorine-2 trifluoroacetyl phenyl)-phthalic diamide and hydrazine hydrate are heated and subjected to reflux in absolute ethyl alcohol, hydrochloric acid and glacial acetic acid are added, and the 4-chlorine-2-(trifluoroacetyl) aniline hydrochloride hydrate is obtained. The method is easy to operate, low in cost and suitable for industrial production, and the total yield is up to 82.2%.