Makrovasküler Komplikasyon Gelişen Diyabetik Hastalarda Risk Faktörlerinin Değerlendirilmesi

2020 
Objecive: In our study, we planned to investigate the risk factors of patients diagnosed with acute myocardial infarction or cerebrovascular event due to macrovascular complications of diabetes mellitus between 2015-2018. Material and Methods: A retrospective study included 48 patients with diabetes mellitus diagnosed with macrovascular complications, the control group consisted of 97 diabetic patients who had no macrovascular complications and that followed-up in our outpatient clinic. In the last 6 months of the patients who developed complications and the patients in the control group, laboratory results were examined and the risk factors were determined according to age, BMI, fasting blood glucose, Hba1C, MPV, RDW, PLT and creatinine parameters.Statistical analysis was performed with SPSS version 17.0 program. Normal distribution of the variables were evaluated according to histogram graphs and Kolmogorov-Smirnov test; In the independent groups, the T test was used to evaluate the nonparametric groups and the Mann Whitney U test was used. Results: As a result of our study, we found a statistically significant relationship with the development of macrovascular complications in diabetic patients, advanced age, progression in HbA1c level, MPV value >11,9 and creatinine levels above 1.2 mg / dl, but gender, BMI, fasting blood glucose, RDW and platelet values were similar in both groups. Conclusion: Based on the data obtained, we think that the follow-up of advanced age, MPV, creatinine, Hba1c values in the follow-up of diabetic patients and the deterioration in these parameters may guide us in terms of the development of macrovascular complications.
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