Toxicity and QSAR of chlorophenols on Lebistes reticulatus

Abstract The 24-h toxicity of 20 substituted chlorophenols upon Lebistes reticulatus has been determined. The biological results have been tentatively connected with several of the following six parameters: logarithm of the octanol-water partition coefficient (log P ); index of molecular connectivity ( 1 χ v ); molecular refraction (RM); perimeter of the efficient section of the molecule ( ΣD ); constants of HAMMET (σ); and melting point ( F ). A correlation is achieved using ΣD and ΣD 2 with a correlation coefficient of 0.943.