Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis

Malavika Raman,Mikhail Sergeev,Maija K. Garnaas,John R. Lydeard,Edward L. Huttlin,Wolfram Goessling,Jagesh V. Shah,J. Wade Harper

Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis

2015

Malavika Raman
Mikhail Sergeev
Maija K. Garnaas
John R. Lydeard
Edward L. Huttlin
Wolfram Goessling
Jagesh V. Shah
J. Wade Harper

Through proteomics, Harper and colleagues identify proteins interacting with UBXD adaptors for the multifunctional AAA-ATPase VCP and reveal a role for UBXN10 in ciliogenesis.

Keywords:

LLC-PK1 Cell
Tumor suppressor proteins
Protein Interaction Map
Cell biology
Cell Cycle Protein
Ciliogenesis
HEK 293 cells
Biology
Cilium
Proteomics
RNA interference
Plasma protein binding
Intraflagellar transport

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