Subinhibitory concentrations of Honokiol reduce α-Hemolysin (Hla) secretion by Staphylococcus aureus and the Hla-induced inflammatory response by inactivating the NLRP3 inflammasome

Na Guo,Zuojia Liu,Zhiqiang Yan,Zonghui Liu,Kun Hao,Chuanbo Liu,Jin Wang

Subinhibitory concentrations of Honokiol reduce α-Hemolysin (Hla) secretion by Staphylococcus aureus and the Hla-induced inflammatory response by inactivating the NLRP3 inflammasome

2019

Na Guo
Zuojia Liu
Zhiqiang Yan
Zonghui Liu
Kun Hao
Chuanbo Liu
Jin Wang

ABSTRACTStaphylococcus aureus (S. aureus) is one of the most serious human pathogens. α-Hemolysin (Hla) secreted by S. aureus is a key toxin for various infections. We herein report that Honokiol, ...

Keywords:

Inflammasome
Secretion
Hemolysin
Microbiology
Staphylococcus aureus
Honokiol
Chemistry
Human leukocyte antigen
Human pathogen
Toxin

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