1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons.

We have used digital fluorescence imaging to compare the ability of the separate enantiomers of trans-ACDP to mobilize intracellular free calcium in cerebellar granule cells, maintained in primary culture. In addition, we have examined the ability of the separate D and L enantiomers of AP3 to antagonise this calcium mobilizing response