Comparison of the mitragynine content of aqueous extracts fromMitragynaspeciosaKorthleaves from two different geographicalareas in Malaysia

It was interesting to find that the concentration of mitragynine in aqueous extracts of MitragynaspeciosaKorthleaves (ketumleaves) from both Penang and Kedah States of Malaysia was merely0.10 µgml -1 and 0.09µgml -1 respectively. There was significant difference observed between the freeze dried yields obtained and the aqueous extracts from Kedah and Penang, 124.0 mg / 60 ml and 262.5 mg/60 ml respectively. Both the aqueous extracts shared the same chemical profile under GCMS chromatogram and contained at least two isomers with 9-methoxy group.