Cognitive deficits in hospitalized and never hospitalized remitted unipolar depressive patients
2010
Background and Objectives: Little is known about the
differences between patients managing depression on an
outpatient basis as compared with hospitalized ones. This study
investigated the performance of attention, executive function
and verbal memory during remission from unipolar depressive
episodes and compare patients with and without history of
hospitalization. Methods: The sample of participants who had
undergone one or more hospitalizations (hospitalized, N = 46)
as well as in a sample without hospitalization (never
hospitalized, N = 46) and controls (N = 92) were used. The
Auditory Verbal Learning Test (AVLT) and the Trail Making Test
(TMT) were administrated to test this hypothesis. Results and
conclusion: The hospitalized sample had similar results in all
four neuropsychological variables in comparison with the never
hospitalized group, and both groups had some lower results in
comparison with controls. In comparison with the controls,
hospitalized sample had mean cognitive deficits of 34%
(28-41%), the never hospitalized group had a mean of 20%
(21-35%). Contrary to previous reports we have found no
meaningful differences between the two patient groups.
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