Intensive uric acid-lowering therapy in CKD patients: the protocol for a randomized controlled trial
2019
Background
Hyperuricemia would be a risk factor for the development/progression of CKD. However, several studies showed U-shape association between serum uric acid level and renal impairment, suggesting that hypouricemia was rather associated with renal dysfunction. Perhaps, there is the optimal target level of serum UA for renal function.
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