CYCLIC VOLTAMMETRIC STUDY OF SOME BIOLOGICALLY ACTIVE DRUGS

This electrochemical study of three different biologically active compounds has been conducted using cyclic voltammetry technique at gold electrode. Losartan Potassium is an antihypertensive drug, while Gemifloxacin is antibacterial and Clarithromycin is primarily bacteriostatic and also has antimicrobial effect. Cyclic voltammetric study has been conducted by using (0.04M) Britton Robinson Buffer as supporting electrolyte with different pH range. For Losartan Potassium pH range of B-R buffer was 8-11 while for Clarithromycin and Gemifloxacin B-R buffer pH range (2-6) has been selected according to the appropriate solubility of these pharmaceutical compounds. Voltammograms of all three biologically active compounds have been recorded at six different scan rates of 20, 100, 200, 300, 400 and 500mV/s.