Dediastereomerization of Dibenzylbutanolides by Plant Cell Cultures

When a mixture of two diastereomers (4R*-3) and (4S*-3) was subjected to plant cell cultures, hydrolysis of acetate and dediastereomerization took place to give a single diastereomer (4R*-1) with 100% diastereomeric excess and 0% enantiomeric excess.