Structure optimization in a series of thiadiazole disperse dyes using a chemometric approach

Structure optimization in a series of thiadiazolyl azo dyes to be used as disperse dyes for polyester fibres has been carried out by a chemometric approach based on experimental design in principal properties and PLS modelling. The thiadiazole nucleus confers a general excellent performance with respect to wet fastness. Light fastness depends on the substitution pattern. Three dyes with especially high fastness values have been identified.