Large-Scale Practical Process of Boc-Protected 4-Fluoro-L- Proline
2020
A large-scale synthesis process of N-Boc-4-fluoro-l-proline (1) from N-Boc-4-hydroxy-l-proline methyl ester (2) using nosyl fluoride (13) as a deoxyfluorinating agent has been developed. An eco-fri...
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