Humoral autoimmune response against S-antigen and IRBP in ocular onchocerciasis.

In this study the involvement of autoimmunity against retinal antigens in developing chorioretinitis was investigated. Serum levels of autoantibodies, directed against human S-antigen and interphotoreceptor retinoid-binding protein, were determined in patients with onchocerciasis and endemic controls from Sierra Leone with the use of an enzyme immunoassay