Semisynthetic Di- and Tri-Functionalized Non-Immunosuppressive Cyclosporin A Derivatives as Potential Anti-HIV 1 Drugs
2004
A regio- and stereoselective synthesis of original semisynthetic di- and tri-functionalized non-immunosuppressive cyclosporins by way of a Barton ester decarboxylation and a C-thioalkylation starting from cyclosporin A (CsA) and [4'-hydroxy-MeLeu] 4 -CsA is described.
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