Epigenetic marks of a stable host-microbiota association in the mammalian gut

To summarize, the results shown here confirms that the host-microbiota interaction is a critical check pint for intestinal inflammation and development. Though, it is still a debate whether the interaction is a cause or consequence of the disease, the results indicate a potential role of epigenetic modification in disease manifestation of UC or postnatal development. The finding might be helpful to support the combinational epigenetic and microbiota based therapies of intestine inflammation.