Synthesis and Screening of α-Xylosides in Human Glioblastoma Cells

Mausam Kalita,Javier Villanueva-Meyer,Yuki Ohkawa,Chakrapani Kalyanaraman,Katharine Chen,Esraa Mohamed,Matthew F. L. Parker,Matthew P. Jacobson,Joanna J. Phillips,Michael J. Evans,David M. Wilson

Synthesis and Screening of α-Xylosides in Human Glioblastoma Cells

2020

Mausam Kalita
Javier Villanueva-Meyer
Yuki Ohkawa
Chakrapani Kalyanaraman
Katharine Chen
Esraa Mohamed
Matthew F. L. Parker
Matthew P. Jacobson
Joanna J. Phillips
Michael J. Evans
David M. Wilson

Glycosaminoglycans (GAGs) such as heparan sulfate and chondroitin sulfate decorate all mammalian cell surfaces. These mucopolysaccharides act as coreceptors for extracellular ligands, regulating ce...

Keywords:

Heparan sulfate
Glioblastoma
Chondroitin sulfate
Prodrug
Glycosaminoglycan
Ligand
Chemistry
mammalian cell
Biochemistry
Extracellular

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