PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

Ana Saavedra,Juan M. García-Martínez,Xavier Xifró,Albert Giralt,Jesús F. Torres-Peraza,Josep M. Canals,Miguel Díaz-Hernández,José J. Lucas,Jordi Alberch,Esther Pérez-Navarro

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

2010

Ana Saavedra
Juan M. García-Martínez
Xavier Xifró
Albert Giralt
Jesús F. Torres-Peraza
Josep M. Canals
Miguel Díaz-Hernández
José J. Lucas
Jordi Alberch
Esther Pérez-Navarro

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

Keywords:

Pleckstrin homology domain
Huntington's disease
Protein kinase B
PI3K/AKT/mTOR pathway
Leucine-rich repeat
Molecular biology
Protein phosphatase 1
Striatum
Biochemistry
Biology
Genetically modified mouse
Huntingtin
Cell biology
Gene silencing
Phosphatase

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