Studies on Synthetic Polypeptide Antigens XV. The Immunochemical Properties of Ferrocenyl-poly Glu58Lys36Tyr6 (No. 2) Conjugates

The metallocenes, of which ferrocene is a prototype, have three distinct advantages for use in metabolic studies: they incorporate radioactive heavy metal atoms with relatively long half-lives; they are biologically stable and probably cannot be reutilized by the animal in any significant amount; and they may become electron-dense if short polymers of the metallocenes are attached to the polypeptide chain.