First synthesis of 3-O-methyl-scyllo-inosamine, a natural product which favors the Rhizobium–Leguminosae symbiosis

Abstract Rhizopine, extracted in small amounts from nodules induced by Sinorhizobium meliloti strain L5-30 infection of alfalfa , was proved to possess the 3- O -methyl-scyllo-inosamine gross structure.