Importance of Sialic Acid Receptor and RIG-I in Innate Immune Response of Poultry

Avian influenza is a viral infection found in domestic poultry and a wide range of other birds. Wild waterfowl and shorebirds are often asymptomatic carriers. RIG-I (retinoic acid-inducible gene I) and Toll like Receptors (TLRs) are well expressed in water fowls. In contract to this RIG-I gene were absent in chicken genome and makes the poultry more susceptible. Avian influenza outbreaks occur in poultry, depopulation (stamping out) of infected flocks is carried out with biosecurity measures.