Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5.
2016
WelO5 is an iron- and 2-oxoglutarate-dependent halogenase involved in welwitindolinone biosynthesis. A collection of X-ray crystal structures reveals the active-site geometry and ligand dynamics required for small-molecule halogenation by WelO5.
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