Belinostat suppresses cell proliferation by inactivating Wnt/β-catenin pathway and promotes apoptosis through regulating PKC pathway in breast cancer

Pengwei Lu,Yuanting Gu,Lin Li,Fang Wang,Xue Yang,Yunqing Yang

Belinostat suppresses cell proliferation by inactivating Wnt/β-catenin pathway and promotes apoptosis through regulating PKC pathway in breast cancer

2019

Pengwei Lu
Yuanting Gu
Lin Li
Fang Wang
Xue Yang
Yunqing Yang

AbstractBelinostat is a histone deacetylase inhibitor drug capable of regulating cell growth in diverse cancers. Nonetheless, little information clarified the role of Belinostat in breast cancer. H...

Keywords:

Materials science
Apoptosis
Breast cancer
Wnt signaling pathway
Histone deacetylase inhibitor
Catenin
Biochemistry
Belinostat
Protein kinase C
Cancer research
Cell growth

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