γ-Promotion of thermal stability and radiolysis mechanism of atenolol β-blocker
2002
Abstract Atenolol (At) β-blocker antihypertensive active ingredient has been investigated for its X-ray diffraction analysis, thermogravimetric analysis (TGA), differential thermal analysis (DTA), IR-absorption spectra and electronic absorption spectra (UV–VIS) before and after exposure to γ-radiation doses. The results obtained indicated high resistance of the material against γ-irradiations. The specific γ-absorbed doses (40 and 60 kGy) induced higher resistance to γ-irradiation. Finally the mechanism of γ-radiolysis is putforward and achieved.
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