Synthesis and Bioactivity of N-Methoxyl-o-aminobenzamide Derivatives
2012
To seek for broad spectra,high efficiency and safe pesticides which work on ryanodines receptor,nine novel N-methoxyl-o-aminobenzamide derivatives were designed and synthesized.Their structures were confirmed by 1H NMR.The preliminary bioactivity evaluation showed that the compounds had 100% insecticidal activities against lepidopte ranpests Mythimna separata at 100 mg/L.At 500 mg/L,most of the compounds exhibited good activities against Homopteran pests Aphis fabae and mite Nephotettix cincticeps.For example,compounds 11a,11c,11e and 11g showed more than 90% insecticidal activities against Aphis fabae;the compound 11e and 11i showed 100% insecticidal activities against Nephotettix cincticeps.All of the title compounds exhibited no acaricidal activities against mite at 500 mg/L.
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