Cobalt-catalyzed synthesis of bromomonofluoroallyl ketones by addition of alkynes and α-bromo-α-fluoroketones
2021
Abstract The first example of Co-catalyzed monofluoroalkylation of alkynes with α-bromo-α-fluoroketones was established for the synthesis of a variety of bromomonofluoroallyl ketones. The reactions were successfully accomplished at room temperature, which were mild and efficient. The mechanism investigation showed that a radical pathway was involved.
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